Mangoes Show Promise in Treating Colon Cancer and IBD

A University of Hyderabad study finds that Mangiferin, a compound in mangoes, shows promise in treating colon cancer and Inflammatory Bowel Disease in mouse models. The researchers demonstrated Mangiferin's antioxidant, anti-inflammatory, and anti-cancer properties in protecting against colitis and colon cancer.

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Dil Bar Irshad
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Mangoes Show Promise in Treating Colon Cancer and IBD

Mangoes Show Promise in Treating Colon Cancer and IBD

Mangoes, specifically, the, compound Mangiferin, have potential in treating colon cancer and Inflammatory Bowel Disease (IBD) in humans. The study, conducted by a team of scientists led by Prof. Reddanna, demonstrated significant results in mouse models.

Why this matters: The findings of this study have significant implications for the treatment of colon cancer and IBD, which affect millions of people worldwide. Further research into the medicinal properties of mangoes could lead to the development of new, more effective treatments for these debilitating diseases.

Mangiferin, a xanthone C-glucoside found in mangoes, has antioxidant, anti-inflammatory, and anti-cancer properties. The compound protected animals from experimentally induced colitis, a form of IBD, by preventing mucosal erosion and infiltration of inflammatory cells. Mangiferin also demonstrated anti-cancer effects on the colon cancer cell line.

The study suggests that mango consumption may help lower the risk of heart problems by reducing lipid levels and inflammation. Dr. Gangadhar, one of the researchers involved, stated, "Our findings provide strong evidence for the potential of Mangiferin in treating IBD and colon cancer. Further studies are needed to develop it as a clinical candidate."

The study assumes importance in light of the increasing cases of IBD, a, chronic, inflammation of the gastrointestinal tract that can lead to cancers if left untreated. IBD affects millions worldwide, with the highest incidence and prevalence in developed countries. Current treatments often have side effects and limited efficacy for severe cases.

The team of researchers at UoH included Dr. Gangadhar, Dr. Suresh Kalangi, Dr. Anil Kotha, and Prof. Reddanna from theSchool of, Life, Sciences. Their groundbreaking work sheds new light on the medicinal properties of mangoes and opens up exciting possibilities for developing novel therapies derived from natural compounds. As research continues, mangoes may prove to be a valuable ally in the fight against debilitating digestive diseases and cancer.

Key Takeaways

  • Mangiferin, a compound in mangoes, may treat colon cancer and Inflammatory Bowel Disease (IBD).
  • Mangiferin has antioxidant, anti-inflammatory, and anti-cancer properties.
  • Mango consumption may lower heart problem risk by reducing lipid levels and inflammation.
  • IBD affects millions worldwide, with limited treatment options and side effects.
  • Further research on Mangiferin could lead to novel, effective treatments for IBD and colon cancer.