Low Testosterone Levels Linked to Higher Risk of Death in Men

A systematic review of 11 studies involving 24,000 male participants found that low testosterone levels increase the risk of cardiovascular disease and mortality. Men with testosterone concentrations below 7.4 nmol/L had a higher risk of all-cause mortality, and those below 5.3 nmol/L had an increased risk of cardiovascular death.

author-image
Trim Correspondents
New Update
Low Testosterone Levels Linked to Higher Risk of Death in Men

Low Testosterone Levels Linked to Higher Risk of Death in Men

low, affect, heart, health, increase, mortality, risk of cardiovascular disease and death. The systematic review and meta-analysis, led by researchers from the University of Western Australia, analyzed data from 11 studies involving over 24,000 male participants.

Why this matters: This study's findings have significant implications for men's health, as low, linked, higher, risk, death. Moreover, understanding the link between testosterone levels and mortality risk can inform strategies to prevent or delay the onset of cardiovascular disease.

cause, mortality, risk, men, low testosterone concentrations below 7.4 nmol/L (213 ng/dL) had a higher risk of all-cause mortality, regardless of luteinizing hormone (LH) concentration. Furthermore, men with testosterone levels below 5.3 nmol/L (153 mg/dL) were at an increased risk of cardiovascular death.

Professor Bu Yeap from UWA's Medical School, the study's lead author, emphasized the significance of the research, stating, "Our research underscores the importance of understanding the impact of sex hormones on health outcomes, particularly in ageing men." The study's rigorous methodology, which included individual patient data meta-analysis and mass spectrometry, was commended in an accompanying editorial from the University of Washington.

While the association between low, affect, heart, health and increased mortality risk is clear, experts caution that the study does not establish a causal relationship. Dr. Karen Eilber, a urologist, notes that it remains unclear whether testosterone levels directly contribute to death or if low testosterone is a sign of overall poor health.

low, levels, men, linked, higher, risk, death have been linked to various health issues in men, including loss of bone density, muscle mass, and libido, as well as increased risk of depression and cognitive decline. Dr. S. Adam Ramin, a board-certified urologist, highlights the importance of maintaining healthy testosterone levels, recommending that men undergo a simple blood test to check their levels, ideally in the mid-morning when testosterone is at its peak.

This pioneering study marks a significant step forward in understanding the link between testosterone levels and mortality risks in men. As the research community continues to explore this relationship, the findings offer valuable insights for future studies and potential interventions to improve men's health outcomes.

Key Takeaways

  • Low testosterone levels increase risk of cardiovascular disease and death.
  • Men with testosterone levels below 7.4 nmol/L have higher risk of all-cause mortality.
  • Testosterone levels below 5.3 nmol/L increase risk of cardiovascular death.
  • Low testosterone linked to various health issues, including depression and cognitive decline.
  • Simple blood test can check testosterone levels, ideally in mid-morning.